diff --git a/README.md b/README.md
index b4efcd5d84ff7407ccd10b5425a74a506c3d3a4c..648984586416a3cec9a287ae1212ba1fe8c2b1e8 100644
--- a/README.md
+++ b/README.md
@@ -95,9 +95,9 @@ acting as a reverse proxy.
 
 If you are not planning to go with Docker or just want to setup a local development environment, then you'll need:
 
-Python 3.7+
-MariaDB
-Virtualenv
+- Python 3.7+
+- MariaDB
+- Virtualenv
 
 ### Installation
 
@@ -107,7 +107,13 @@ Create a virtual environment for your Python dependencies:
 virtualenv -p python3.7 python
 ```
 
-Install the required dependencies:
+To activate that environment, run
+
+```bash
+source python/bin/activate
+```
+
+Install the required dependencies
 
 ```bash
 pip3 install -r requirements.txt
@@ -205,18 +211,63 @@ Then run this from the root directory:
 ./run.sh api
 ```
 
+If this is succeeding, you can now proceed to configure Engine API to run as a system daemon using [Systemd](#running-with-systemd) or
+[Supervisor](#running-with-supervisor).
+
 ### Running with Systemd
 
-**tbd**
+The Systemd unit file configuration expects to be running under the user `engineuser`. To create such user type:
+
+```shell
+    sudo adduser engineuser
+    sudo adduser engineuser sudo
+```
+
+Copy the systemd unit file in `./config/sample/systemd` to `/etc/systemd/system`. This configuration file is expecting you to have
+Engine API installed under `/opt/aura/engine-api` and `engineuser` owning the files.
+
+Next login to `engineuser` and give it permissions to the unit file
+
+```shell
+  su engineuser
+  sudo chmod 644 /etc/systemd/system/aura-engine-api.service
+```
+
+Let's start the service
+
+```shell
+sudo systemctl start aura-engine-api
+```
+
+And check if it has started successfully
+
+```shell
+sudo systemctl status aura-engine-api
+```
+
+If you experience issues and need more information, check the syslog while starting the service
+
+```shell
+tail -f /var/log/syslog
+```
+
+You can stop or restart the service with one of these
+
+```shell
+sudo systemctl stop aura-engine-api
+sudo systemctl restart aura-engine-api
+```
+
+Note, any requirements from the [Installation](#installation) step need to be available for that user.
 
 ### Running with Supervisor
 
-Alternatively to Systemd you can start Engine API using [Supervisor](http://supervisord.org/). In `./config/sample/supervisor/aura-engine-api.conf` you can find a example.
-Supervisor configuration file.
+Alternatively to Systemd you can start Engine API using [Supervisor](http://supervisord.org/). In `./config/sample/supervisor/aura-engine-api.conf` you
+can find an example Supervisor configuration file. Follow the initial steps of the Systemd setup.
 
 ### Running with Docker
 
-To run the server on a Docker container, please execute the following from the root directory:
+To run the server in a Docker container, please execute the following from the root directory:
 
 ```bash
 # Building the image